Breast Cancer

Project – Monitoring the breast tumour microenvironment following radiotherapy using super-resolution ultrasound and functional MRI.

This project aims to develop robust quantitative parameters to detect biological changes before tumour size changes, in the hope of identifying response, resistance or relapse earlier than is currently possible.

The figures below show normal breast microvasculature and the breast tumour microvasculature before treatment. The tumour microvasculature is seen to be more densely vascularized and chaotic. The breast tumour microvasculature 12 months post radiotherapy treatment visually appears to have normalised.

Normal breast microvasculature, the breast tumour microvasculature before treatment and 12 months post radiotherapy treatment.