3D Coronary ULM

Project – 3D Coronary Ultrasound Localisation Microscopy

ULM can measure parameters such as vascular tortuosity and blood flow with unprecedented detail and accuracy. A limitation of 2D ULM is out of plane flow, complex three-dimensional vasculature and motion. This limits the ability of ULM to measure myocardial microvasculature structures. We demonstrate the feasibility of deep 3D ULM with a matrix array in a large porcine model with realistic motion to narrow the translational gap between research and meaningful clinical applications.

Microvasculature of the myocardium in an ex vivo porcine heart.